Irene Filippi
C.V.

Radi M., Dreassi E., Brullo C., Crespan E., Tintori C., Bernardo V., Valoti M., Zamperini C., Daigl H., Musumeci F., Carraro F., Naldini A., Filippi I., Maga G., Schenone S. and Botta M., (2011) Design, synthesis, biological activity and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study, J Med Chem, Submitted.

Naldini A., Filippi I., Miglietta D., Moschetta M., Giavazzi R., and Carraro F., (2010) Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α, Eur J Cancer, 46 (18): 3400-3408.

Dreassi E., Zizzari A.T., Mori M., Filippi I., Belfiore A.Naldini A., Carraro F., Santucci A., Schenone S., and Botta M., (2010) 2-Hydroxypropyl-β-cyclodextrin complexation strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors, Eur J Med Chem, 45 (12): 5958-5964.

Cappelli A., Valenti S., Mancini A., Giuliani G., Anzini M., Altieri S., Bortolussi S., Ferrari C., Clerici A., Zonta C., Carraro F., Filippi I., Giorgi G., Donati A., Ristori S., Vomero S., Concas A., Biggio G., (2010) Carborane-Conjugated 2-Quinolinecarboxamide Ligands of the Translocator Protein for Boron Neutron Capture Therapy, Bioconjugate Chemistry, 21 (12): 2213-2221.

Moretti S., Nassini R., Prignano F., Pacini A., Materazzi S., Naldini A., Simoni A., Baroni G., Pellerito S., Filippi I., Lotti T., Geppetti P., Massi D., (2009) Protease-activated receptor-2 downregulation is associated to vitiligo lesions, Pigment Cell Melanoma Res, 22 (3): 335-338.

Naldini A., Filippi I., Ardinghi C., Silini A., Giavazzi R., and Carraro F., (2009) Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells, Eur J Cancer, 45 (3): 454-460.

Pallottini V., Guantario B., Martini C., Totta P., Filippi I., Carraro F., Trentalance A., (2008) Regulation of HMG-CoA reductase expression by hypoxia, J Cell Biochem, 104 (3): 701-709.

Naldini A., Morena E., Filippi I., Pucci A., Bucci M., Cirino G., and Carraro F., (2006) Thrombin inhibits interferon-gamma production in human peripheral blood mononuclear cells by promoting a Th-2 profile, Journal of Interferon & Cytokine research, 26 (11): 793-799.