Massimo Valoti
C.V.

Bellik L, Dragoni S, Pessina F, Sanz E, Unzeta M,  Valoti M. Antioxidant properties of PF9601N, a novel MAO-B inhibitor: assessment of its ability to interact with reactive nitrogen species. Acta Biochim Pol. 2010;57:235-9.

Anzini M, Chelini A, Mancini A, Cappelli A, Frosini M, Ricci L,  Valoti M, Magistretti J, Castelli L, Giordani A, Makovec F, Vomero S. Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases. J Med Chem. 2010;53:734-44.

Ricci L,  Valoti M, Sgaragli G, Frosini M. Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage. Eur J Pharmacol. 2009;621 26-32.

D'Elia P, De Matteis F, Dragoni S, Shah A, Sgaragli G,  Valoti M. DP7, a novel  dihydropyridine multidrug resistance reverter, shows only weak inhibitory activity on human CYP3A enzyme(s). Eur J Pharmacol. 2009;614:7-13.

Maiani G, Castón MJ, Catasta G, Toti E, Cambrodón IG, Bysted A, Granado-Lorencio F, Olmedilla-Alonso B, Knuthsen P,  Valoti M, Böhm V, Mayer-Miebach E, Behsnilian D, Schlemmer U. Carotenoids: actual knowledge on food sources, intakes, stability and bioavailability and their protective role in humans. Mol Nutr Food Res. 2009;53 Suppl 2:S194-218.

Blanco Garcia J, Aldinucci C, Maiorca SM, Palmi M,  Valoti M, Buonocore G, Pessina GP. Physiopathological effects of the NO donor 3-morpholinosydnonimine on rat cortical synaptosomes. Neurochem Res. 2009;34:931-41.

Della Torre C, Corsi I, Arukwe A,  Valoti M, Focardi S. Interactions of 2,4,6-trinitrotoluene (TNT) with xenobiotic biotransformation system in European  eel Anguilla anguilla (Linnaeus, 1758). Ecotoxicol Environ Saf. 2008

Sanz E, Quintana A, Battaglia V, Toninello A, Hidalgo J, Ambrosio S,  Valoti M, Marco JL, Tipton KF, Unzeta M. Anti-apoptotic effect of Mao-B inhibitor PF9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] is mediated by p53 pathway inhibition in MPP+-treated SH-SY5Y human dopaminergic cells. J Neurochem. 2008;105:2404-17.

Dragoni S, Materozzi G, Pessina F, Frosini M, Marco JL, Unzeta M, Sgaragli G,   Valoti M. CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes. J Pharm Pharm Sci. 2007;10(4):473-85.

Ferrini S, Fusi S, Ponticelli F,  Valoti M. Heteroaryl-substituted phenols as  potential antioxidants. J Pharm Pharmacol. 2007;59:829-35.

Pessina F, Valeri A, Dragoni S,  Valoti M, Sgaragli G. Gender-related neuronal and smooth muscle damage of guinea pig isolated urinary bladder from anoxia-glucopenia and reperfusion injury and its relationship to glycogen content. Neurourol Urodyn. 2007;26:416-23.

Ricci L,  Valoti M, Sgaragli G, Frosini M. Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain  slices. Eur J Pharmacol. 2007;5610:80-4.

Marini S, Nannelli A, Sodini D, Dragoni S,  Valoti M, Longo V, Gervasi PG. Expression, microsomal and mitochondrial activities of cytochrome P450 enzymes in brain regions from control and phenobarbital-treated rabbits. Life Sci. 2007;80:910-7.

Cappelli A, Pericot Mohr G, Giuliani G, Galeazzi S, Anzini M, Mennuni L, Ferrari F, Makovec F, Kleinrath EM, Langer T,  Valoti M, Giorgi G, Vomero S. Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds. J Med Chem. 2006;49:6451-64.

Fusi F, Saponara S,  Valoti M, Dragoni S, D'Elia P, Sgaragli T, Alderighi D, Kawase M, Shah A, Motohashi N, Sgaragli G. Cancer cell permeability-glycoprotein  as a target of MDR reverters: possible role of novel dihydropyridine derivatives. Curr Drug Targets. 2006;7:949-59.

Dragoni S, Porcari V, Travagli M, Castagnolo D,  Valoti M. Antioxidant properties of propargylamine derivatives: assessment of their ability to scavenge peroxynitrite. J Pharm Pharmacol. 2006;58:561-5.

Frosini M, Ricci L, Saponara S, Palmi M,  Valoti M, Sgaragli G. GABA-mediated  effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature  and gross motor behavior. Amino Acids. 2006;30:233-42.

Ricci L, Frosini M, Gaggelli N, Valensin G, Machetti F, Sgaragli G,  Valoti M. Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis. Biochem Pharmacol. 2006;71:1510-9.

Dragoni S, Gee J, Bennett R,  Valoti M, Sgaragli G. Red wine alcohol promotes  quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro. Br J Pharmacol. 2006;147:765-71.

Brizzi A, Brizzi V,  Valoti M. Synthesis and in vitro pharmacological activity of oxypropanol analogs of labetalol. Farmaco. 2005;60:105-11.