Giampietro Sgaragli
C.V.

  1. Castagnolo D, Contemori L, Maccari G, Avramova SI, Neri A, Sgaragli G, Botta M. From Natural Taxuspine X to Structurally Simplified Taxane Analogues: Synthesis of Non-Natural Natural Products with Remarkable P-glycoprotein Inhibitory Activity. ACS Medicinal Chemistry Letters 2010. Accepted for publication (DOI: 10.1021/ml100118k).
  2. Fusi, F., Cavalli, M., Mulholland, D., Crouch, N., Coombes, P., Dawson, G., et al. (2010). Cardamonin is a bifunctional vasodilator that inhibits Cav1.2 current and stimulates KCa1.1 current in rat tail artery myocytes. Journal of Pharmacology and Experimental Therapeutics, 332(2), 531-540.   
  3. Ricci, L., Valoti, M., Sgaragli, G., & Frosini, M. (2009). Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage. European Journal of Pharmacology, 621(1-3), 26-32. 
  4. Valeri, A., Ceccarelli, I., Fiorenzani, P., Aloisi, A. M., Sgaragli, G., & Pessina, F. (2009). Effects of 17β-estradiol on rat urinary bladder: Gender differences in anoxia-glucopenia and reperfusion damage.Neurourology and Urodynamics, 28(6), 535-541.
  5. D'Elia, P., De Matteis, F., Dragoni, S., Shah, A., Sgaragli, G., & Valoti, M. (2009). DP7, a novel dihydropyridine multidrug resistance reverter, shows only weak inhibitory activity on human CYP3A enzyme(s). European Journal of Pharmacology, 614(1-3), 7-13.
  6. Valeri, A., Brain, K. L., Young, J. S., Sgaragli, G., & Pessina, F. (2009). Effects of 17β-oestradiol on rat detrusor smooth muscle contractility. Experimental Physiology, 94(7), 834-846.
  7. Bova, S., Saponara, S., Rampa, A., Gobbi, S., Cima, L., Fusi, F., et al. (2009). Anthracene based compounds as new L-type Ca2+ channel blockers: Design, synthesis, and full biological profile. Journal of Medicinal Chemistry, 52(5), 1259-1262.
  8. Martelli, C., Alderighi, D., Coronnello, M., Dei, S., Frosini, M., Bozec, B. L., et al. (2009). N,N-bis(cyclohexanol)amine aryl esters: A new class of highly potent transporter-dependent multidrug resistance inhibitors. Journal of Medicinal Chemistry, 52(3), 807-817. 
  9. Saponara, S., Sgaragli, G., & Fusi, F. (2008). Quercetin antagonism of bay K 8644 effects on rat tail artery L-type Ca2+ channels. European Journal of Pharmacology, 598(1-3), 75-80.
  10. Ricci, L., Valoti, M., Sgaragli, G., & Frosini, M. (2008). Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: An hormetic dose-response effect. American Journal of Pharmacology and Toxicology, 3(1), 157-164.
  11. Mortensen, A., Sorensen, I. K., Wilde, C., Dragoni, S., Mullerová, D., Toussaint, O., et al. (2008). Biological models for phytochemical research: From cell to human organism. British Journal of Nutrition, 99(E-SUPPL. 1), ES118-ES126.
  12. Avramova, S. I., Galletti, E., Renzulli, M. L., Giorgi, G., Sgaragli, G., Alderighi, D., et al. (2008). Synthesis of an original oxygenated taxuspine X analogue: A versatile "non-natural" natural product with remarkable P-gp modulating activity. ChemMedChem, 3(5), 745-748.
  13. Fusi, F., Ferrara, A., Koorbanally, C., Crouch, N. R., Mulholland, D. A., & Sgaragli, G. (2008). Vascular myorelaxing activity of isolates from south african hyacinthaceae partly mediated by activation of soluble guanylyl cyclase in rat aortic ring preparations. Journal of Pharmacy and Pharmacology, 60(4), 489-497.
  14. Lorenzi, B., Pessina, F., Lorenzoni, P., Urbani, S., Vernillo, R., Sgaragli, G., et al. (2008). Treatment of experimental injury of anal sphincters with primary surgical repair and injection of bone marrow-derived mesenchymal stem cells. Diseases of the Colon and Rectum, 51(4), 411-420.
  15. Fusi, F., Ferrara, A., Zalatnai, A., Molnar, J., Sgaragli, G., & Saponara, S. (2008). Vascular activity of two silicon compounds, ALIS 409 and ALIS 421, novel multidrug-resistance reverting agents in cancer cells. Cancer Chemotherapy and Pharmacology, 61(3), 443-451.