Fabio Carraro
C.V.

1. Cappelli, A., S. Valenti, A. Mancini, G. Giuliani, M. Anzini, S. Altieri, S. Bortolussi, C. Ferrari, A. M. Clerici, C. Zonta, F. Carraro, I. Filippi, G. Giorgi, A. Donati, S. Ristori, S. Vomero, A. Concas, and G. Biggio. 2010. Carborane-Conjugated 2-Quinolinecarboxamide Ligands of the TranslocatorProtein for BoronNeutronCaptureTherapy. BioconjugChem.

2.    Dreassi, E., A. T. Zizzari, M. Mori, I. Filippi, A. Belfiore, A. Naldini, F. Carraro, A. Santucci, S. Schenone, and M. Botta. 2010. 2-Hydroxypropyl-+¦-cyclodextrinstronglyimproves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidinesSrc-Abldualinhibitors. Eur J MedChem.

3.    Naldini, A., I. Filippi, D. Miglietta, M. Moschetta, R. Giavazzi, and F. Carraro. 2010. Interleukin-1beta regulates the migratorypotential of MDAMB231 breastcancercellsthrough the hypoxia-inducible factor-1alpha. Eur J Cancer.

4.    Silini, A., C. Ghilardi, C. Ardinghi, S. Bernasconi, P. Oliva, F. Carraro, A. Naldini, M. R. Bani, and R. Giavazzi. 2009. Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and isassociated to theirmetastaticphenotype. ClinExpMetastasis 27:43.

5.    Naldini, A., E. Morena, A. Pucci, M. Pellegrini, C. T. Baldari, P. G. Pelicci, M. Presta, D. Ribatti, and F. Carraro. 2009. The adaptorprotein p66Shc is a positive regulator in the angiogenicresponseinduced by hypoxic T cells. J LeukocBiol 87:365.

6.    Falchi, F., F. Manetti, F. Carraro, A. Naldini, G. Maga, E. Crespan, S. Schenone, O. Bruno, C. Brullo, and M. Botta. 2009. 3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors. ChemMedChem 4:976.

7.    Naldini, A., I. Filippi, C. Ardinghi, A. Silini, R. Giavazzi, and F. Carraro. 2008. Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells. Eur J Cancer 45:454.

8.    Naldini, A., E. Morena, M. Fimiani, G. Campoccia, V. Fossombroni, and F. Carraro. 2008. The effects of autologous platelet gel on inflammatory cytokine response in human peripheral blood mononuclear cells. Platelets 19:268.

9.    Pallottini, V., B. Guantario, C. Martini, P. Totta, I. Filippi, F. Carraro, and A. Trentalance. 2008. Regulation of HMG-CoA reductase expression by hypoxia. J Cell Biochem 104:701.

10.    Manetti, F., C. Brullo, M. Magnani, F. Mosci, B. Chelli, E. Crespan, S. Schenone, A. Naldini, O. Bruno, M. L. Trincavelli, G. Maga, F. Carraro, C. Martini, F. Bondavalli, and M. Botta. 2008. Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines. J MedChem 51:1252.

11.    Schenone, S., C. Brullo, O. Bruno, F. Bondavalli, L. Mosti, G. Maga, E. Crespan, F. Carraro, F. Manetti, C. Tintori, and M. Botta. 2008. Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines. Eur J MedChem 43:2665.

12.    Bocci, V., C. Aldinucci, F. Mosci, F. Carraro, and G. Valacchi. 2007. Ozonation of Human Blood Induces a Remarkable Upregulation of Heme Oxygenase-1 and Heat Stress Protein-70. MediatorsInflamm 2007.

13.    Naldini, A., C. Ardinghi, D. Massi, M. Santucci, A. Franchi, F. Tarantini, P. Geppetti, G. Cirino, and F. Carraro. 2007. A ribonuclease protection assay-based approach for analysis of angiogenic gene expression in archival tissues. DiagnMolPathol 16:147.

14.    Boraldi, F., G. Annovi, F. Carraro, A. Naldini, R. Tiozzo, P. Sommer, and D. Quaglino. 2007. Hypoxia influences the cellular cross-talk of human dermal fibroblasts. A proteomicapproach. BiochimBiophys Acta 1774:1402.

15.    Carraro, F., A. Pucci, M. Pellegrini, P. G. Pelicci, C. T. Baldari, and A. Naldini. 2007. p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells. J Cell Physiol 211:439.

16.    Manetti, F., A. Pucci, M. Magnani, G. A. Locatelli, C. Brullo, A. Naldini, S. Schenone, G. Maga, F. Carraro, and M. Botta. 2007. Inhibition of Bcr-Abl phosphorylation and induction of apoptosis by pyrazolo[3,4-d]pyrimidines in human leukemia cells. ChemMedChem 2:343.

17.    Naldini, A., E. Morena, I. Filippi, A. Pucci, M. Bucci, G. Cirino, and F. Carraro. 2006. Thrombin inhibits IFN-gamma production in human peripheral blood mononuclear cells by promoting a Th2 profile. J Interferon Cytokine Res 26:793.

18.    Naldini, A., D. Leali, A. Pucci, E. Morena, F. Carraro, B. Nico, D. Ribatti, and M. Presta. 2006. Cutting edge: IL-1beta mediates the proangiogenic activity of osteopontin-activated human monocytes. J Immunol 177:4267.

19.    Carraro, F., A. Naldini, A. Pucci, G. A. Locatelli, G. Maga, S. Schenone, O. Bruno, A. Ranise, F. Bondavalli, C. Brullo, P. Fossa, G. Menozzi, L. Mosti, M. Modugno, C. Tintori, F. Manetti, and M. Botta. 2006. Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation. J MedChem 49:1549.

20.    Franchi, A., D. Massi, M. Santucci, E. Masini, D. R. Degl'Innocenti, L. Magnelli, E. Fanti, A. Naldini, C. Ardinghi, F. Carraro, and O. Gallo. 2006. Inducible nitric oxide synthase activity correlates with lymphangiogenesis and vascular endothelial growth factor-C expression in head and neck squamous cell carcinoma. J Pathol 208:439.

21.    Naldini, A., C. Bernini, A. Pucci, and F. Carraro. 2005. Thrombin-mediated IL-10 up-regulation involves protease-activated receptor (PAR)-1 expression in human mononuclear leukocytes. J LeukocBiol 78:736.

22.    Massi, D., A. Naldini, C. Ardinghi, F. Carraro, A. Franchi, M. Paglierani, F. Tarantini, S. Ketabchi, G. Cirino, M. D. Hollenberg, P. Geppetti, and M. Santucci. 2005. Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma. Hum Pathol 36:676.

23.    Naldini, A., and F. Carraro. 2005. Role of inflammatory mediators in angiogenesis. Curr Drug Targets Inflamm Allergy 4:3.

24.    Naldini, A., F. Carraro, C. T. Baldari, S. R. Paccani, C. Bernini, M. J. Keherly, and D. H. Carney. 2004. The thrombin peptide, TP508, enhances cytokine release and activates signaling events. Peptides 25:1917.

25.    Cavarra, E., F. Carraro, S. Fineschi, A. Naldini, B. Bartalesi, A. Pucci, and G. Lungarella. 2004. Early response to bleomycin is characterized by different cytokine and cytokine receptor profiles in lungs. Am J PhysiolLung Cell MolPhysiol 287:L1186-L1192.

26.    Carraro, F., A. Pucci, A. Naldini, S. Schenone, O. Bruno, A. Ranise, F. Bondavalli, C. Brullo, P. Fossa, G. Menozzi, L. Mosti, F. Manetti, and M. Botta. 2004. Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells. J MedChem 47:1595.

27.    Pacini, S., M. Pellegrini, E. Migliaccio, L. Patrussi, C. Ulivieri, A. Ventura, F. Carraro, A. Naldini, L. Lanfrancone, P. Pelicci, and C. T. Baldari. 2004. p66SHC Promotes Apoptosis and Antagonizes Mitogenic Signaling in T CellsGÇá. Mol Cell Biol 24:1747.

28.    Naldini, A., A. Pucci, D. H. Carney, G. Fanetti, and F. Carraro. 2002. Thrombin enhancement of interleukin-1 expression in mononuclear cells: involvement of proteinase-activated receptor-1. Cytokine 20:191.

29.    Naldini, A., D. H. Carney, A. Pucci, and F. Carraro. 2002. Human alpha-thrombin stimulates proliferation of interferon-gamma differentiated, growth-arrested U937 cells, overcoming differentiation-related changes in expression of p21CIP1/WAF1 and cyclin D1. J Cell Physiol 191:290.