Keith Lawrence Brain
C.V.

Brading AF & Brain KL. (2010). Ion Channel Modulators. In Uropharmacology, ed. Andersson KE & Michel MC, pp. In press. Springer.
Brain KL. (2010). Parasympathetic cholinergic transmission, minus the vesicles. Exp Physiol 95, 263-264.

Parker LK, Shanks JA, Kennard JAG & Brain KL. (2010). Dynamic monitoring of NET activity in mature murine sympathetic terminals using a fluorescent substrate. Br J Pharmacol 159, 797-807.

Brain KL. (2009). Neuroeffector Ca2+ transients for the direct measurement of purine release and indirect measurement of co-transmitters. Exp Physiol 94, 25-30.

Rahman F, Manchanda R & Brain KL. (2009). Prejunctional and postjunctional actions of heptanol and 18β-glycyrretinic acid in the rodent vas deferens. Auton Neurosci 148, 69–75.

Valeri A, Brain KL, Young JS, Sgaragli G & Pessina F. (2009). Effects of 17β-estradiol on rat detrusor smooth muscle contractility. Exp Physiol 94, 834-846.

Young JS, Amos RJ & Brain KL. (2009). Focal Ca2+ transient detection in smooth muscle. Journal of Visualized Experiments 28, doi: 10.3791/1247.

Brain KL & Cunnane TC. (2008). Bretylium abolishes neurotransmitter release without necessarily abolishing the nerve terminal action potential in sympathetic terminals. Br J Pharmacol 153, 831–839.

Young JS, Meng E, Cunnane TC & Brain KL. (2008). Efferent purinergic neurotransmission in the mouse urinary bladder. J Physiol 586, 5743-5755.

Zhu HL, Brain KL, Aishima M, Shibata A, Young JS, Sueishi K & Teramoto N. (2008). Actions of two main metabolites of propiverine (M-1 and M-2) on voltage-dependent L-Type Ca2+ currents and Ca2+ transients in murine urinary bladder myocytes. J Pharm Exp Ther 324, 118-127.

Williams DJ, Brain KL & Cunnane TC. (2007). The effect of epibatidine on spontaneous and evoked neurotransmitter release in the mouse and guinea pig isolated vas deferens. Br J Pharmacol 150, 906-912.

Young JS, Brain KL & Cunnane TC. (2007a). Electrical and optical study of nerve impulse-evoked ATP-induced, P2X-receptor-mediated sympathetic neurotransmission at single smooth muscle cells in mouse isolated vas deferens. Neuroscience 148, 82-91.

Young JS, Brain KL & Cunnane TC. (2007b). The origin of the skewed amplitude distribution of spontaneous excitatory junction potentials in poorly coupled smooth muscle cells. Neuroscience 145, 153-161.

Brain KL, Kay J & Shine B. (2006). Measurement of urinary metanephrines to screen for pheochromocytoma in an unselected hospital referral population. Clinical Chemistry 52, 2060-2064.
Webster RG, Brain KL, Wilson RH, Grem JL & Vincent A. (2005).

Oxaliplatin induces hyperexcitability at motor and autonomic neuromuscular junctions through effects on voltage-gated sodium channels. British Journal of Pharmacology 146, 1027-1039.

Brain KL, Cuprian AM, Williams DJ & Cunnane TC. (2003). The sources and sequestration of Ca2+ contributing to neuroeffector Ca2+ transients in the mouse vas deferens. J Physiol 553, 627-635.

Brain KL, Jackson VM, Trout SJ & Cunnane TC. (2002). Intermittent ATP release from nerve terminals elicits focal smooth muscle Ca2+ transients in mouse vas deferens. J Physiol 541, 849-862.

Brain KL, Trout SJ, Jackson VM, Dass N & Cunnane TC. (2001). Nicotine induces calcium spikes in single nerve terminal varicosities: A role for intracellular calcium stores. Neuroscience 106, 395-403.

Jackson VM, Trout SJ, Brain KL & Cunnane TC. (2001). Characterization of action potential-evoked calcium transients in mouse postganglionic sympathetic axon bundles. J Physiol 537, 3-16.

Lengyel I, Olesen LE, Nichol KA, Brain KL, Wang X, Robinson PJ, Bennett MR & Rostas JAP. (1999). Phosphorylation of proteins in chick ciliary ganglion under conditions that induce long-lasting changes in synaptic transmission: phosphoprotein targets for nitric oxide action. Neuroscience 90, 607-619.

O'Connor SC, Brain KL & Bennett MR. (1999). Individual sympathetic varicosities possess different sensitivities to alpha 2 and P2 receptor agonists and antagonists in mouse vas deferens. Br J Pharmacol 128, 1739-1753.

Bennett MR, Cheung A & Brain KL. (1998). Sympathetic neuromuscular transmission at a varicosity in a syncytium. Microsc Res Tech 42, 433-450.

Brain KL & Bennett MR. (1998). Calcium transients evoked by action potentials in the somata of chick ciliary neurons. J Auton Nerv Syst 71, 120-133.

Lin YQ, Brain KL & Bennett MR. (1998). Calcium in sympathetic boutons of rat superior cervical ganglion during facilitation, augmentation and potentiation. J Auton Nerv Syst 73, 26-37.

Bennett MR & Brain KL. (1997). Autonomic synaptic transmission at single boutons and calyces. J Neurocytol 26, 577-603.

Brain KL & Bennett MR. (1997). Calcium in sympathetic varicosities of mouse vas deferens during facilitation, augmentation and autoinhibition. J Physiol 502, 521-536.

Brain KL, Cottee LJ & Bennett MR. (1997). Varicosities of single sympathetic nerve terminals possess syntaxin zones and different synaptotagmin N-terminus labelling following stimulation. J Neurocytol 26, 491-500.

Lin YQ, Brain KL, Nichol KA, Morgan JJ & Bennett MR. (1996). Vesicle-associated proteins and calcium in nerve terminals of chick ciliary ganglia during development of facilitation. J Physiol 497, 639-656.

Brain KL & Bennett MR. (1995). Calcium in the nerve terminals of chick ciliary ganglia during facilitation, augmentation and potentiation. J Physiol 489, 637-648.
Sheppard CJR, Gu M, Brain KL & Zhou H. (1994). Influence of spherical aberration on axial imaging of confocal reflection microscopy. Applied Optics 33, 616-624.