- Experimental model of hypoxic-ischemic brain damage: evaluation of intracellular and plasmatic free iron and evaluation of new chelating molecules
- Experimental model of retinopathy in prematurity: evaluation of tissue lipid peroxidation.
- Clinical and experimental use of erythropoietin in infants with hypoxic-ischemic-hemorrhagic encephalopathy
- Evaluation of free radical damage in prenatal and perinatal hypoxic-ischemic kidney injury
- Serum concentrations of cytokines in neonates at different dietary regimens: role in food allergy
- Evaluation of lipoperoxidative risk during feeding with LC-PUFA rich milk and evaluation of nutritional factors and supplements as protective agents against oxidative stress

- Oxidative stress and its biomedical implications in perinatal pathophysiology
- Oxidative stress and its biomedical implications in human pathology: in diabetes mellitus, in cerebral hypoxic damage and in Rett Syndrome

- Biological mechanisms of the diabetogenic action of dioxin
- Protective mechanisms of plant components against cytokine-induced pancreatic β-cell dysfunction and death
- Multilayer nanoencapsulation of anti-inflammatory nanoparticles and their nanoparticle-driven displacement in pancreatic islets transplantation for type 1 diabetes treatment

- Animal models of pulmonary emphysema for the study of Chronic Obstructive Pulmonary Disease (COPD)
- Role of isoprostanes in the pathogenesis of hepatic and pulmonary fibrosis
- In vivo and in vitro models of rheumatoid arthritis for the evaluation of new drugs
- Protective effect of physical training on ozone toxicity

- Gas phase ion chemistry: structural characterization and reactivity of bioorganic molecules, amino acids and peptides by advanced mass spectrometry
- Crystal and molecular structure determination of heterocycles of biological interest

- Role of calpains in apoptotic cell death of tumor cells
- The autophagic response as a protective mechanism against apoptosis induced by genotoxic drugs in human melanoma cells
- Role of p53 modulation in the cross-talk between apoptosis and autophagy
- Biochemical and functional characterization of novel splice variants of muscle-specific calpain 3 in human cutaneous melanoma: role in tumor progression and in proliferation/apoptosis equilibrium
- Chemotherapeutic drugs complexed to novel synthetic polymers (hydrogels) responsive to chemical-physical stimuli: evaluation of citotoxicity in tumor cells
- Apoptotic-like biochemical alterations in erythrocytes from type 2 diabetes patients

- Expression of membrane gamma-glutamyltransferase activity and resistance/sensitivity of cancer cells to chemotherapeutic agents
- Pro- and anti-inflammatory actions of neutrophilic gamma-glutamyltransferase in lung inflammation exudates
- Mechanisms in insudation and pathogenetic roles of serum gamma-glutamyltransferase in atherosclerotic lesions

- Neonatal oxidative stress: Non-protein-bound iron, F2-isoprostanes and relationships among plasmatic oxidative parameters
- Experiemental model of neonatal hypoxic encephalopathy: F2-isoprostanes and F4-neuroprostanes
- Diabetes: oxidative stress and erythrocyte senescence
- F2-isoprostanes in human hepatic pathologies and in experimental models
- Experimental models of intoxication with nanoparticles in rat: oxidative stress induced by silica nanoparticles doped with cadmium in rat
- Pathogenesis of classic Rett syndrome: hypoxia-induced oxidative stress

- Pathophysiology of biological membranes in metabolic diseases
- Role of nutrients and antioxidants in the defence against oxidative stress
- Structural and functional aspects of heat shock proteins

- Biochemical chracterization of therapeutic properties of Mucuna Pruriens plant
- Production and Characterization of Monoclonal Antibodies to Epitope of Proteic Isoforms
- Allergy of protein wheat, ipersensibility of gluten, celiac disease: proteomic patterns
- Proteomic Characterization of Aqueous Humor in Retinoblastoma
- Biochemical/Proteomic Investigation on Serum and Intestinal Mucosa in Patients affected by colorectal neoplasia
- Proteomic Investigation of Human Sclerodermic Fibroblasts
- In vitro exposition of human osteoarthritis chondrocytes to ELF and TAMMEF electromagnetic fields: proteomic and biochemical analysis on cultures treated with specific drugs
- Diagnosis and gene/enzyme therapy monitoring of ADA/PNP SCID
- Pathophysiology and autoimmune disorders
- Retroviral vectors biology and in vivo activity of hsc/limphocytes evaluated by retroviral inserctions
- Regional Project for the Unification of Reference Values in Clinical Biochemistry: development of a data mining algorithm

- Evaluation in vitro and in vivo of the antioxidant properties of coenzyme Q
- Relationship between coenzyme Q10 and endothelial function
- Peroxidation of plasma lipoproteins

- Morphological and structural characterization of lymphatic vessels in peripheral nerve by novel lymphatic vessels markers
- Role of the endothelin system in inflammatory neuropathies
- Expression of the angiogenic factor VEGF-A and its antiangiogenic variant VEGF-A165b in inflammatory miopathies

- Genetic predisposition and lung fibroblast global gene expression in idiopathic and connective tissue disease-associated interstitial lung diseases
- Study of vascular and lymphatic morphology and distribution in IPF and CTD-associated lung fibrosis
- Serum and bronchoalveolar lavage biomarkers as predictors of disease progression in interstitial lung diseases

- Isolation and culture of blood and lymphatic endothelial cells from human and from bovine aorta and thoracic duct
- Systemic sclerosis: Immunohistochemical and morphometric study of lymphatic vessels
- Deposition of fibrillin and associated molecules in the extracellular matrix by cultured blood and lymphatic endothelial cells in the presence of sera from systemic sclerosis patients
- Interactions of blood and lymphatic endothelial cells with the extracellular matrix: immunohistochemical evaluation of focal contact molecules
- Bioengineering in cardiovascular fields: culture of endothelial cells on microstructured surfaces and inside polysaccharidic hydrogels with the "amber effect" technique
- Use of stem cells in the reconstruction of sphincters: experimental model in rat