DOCTORATE in GENETICS, ONCOLOGY and CLINICAL MEDICINE (GenOMeC)
DOTTORATO DI RICERCA IN GENETICA ONCOLOGIA E MEDICINA CLINICA

UNIVERSITA' DEGLI STUDI  DI SIENA

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Publications during the PhD program

 
Defina Marzia    
 

1) Cutaneous myeloma and bortezomib.

Gozzetti A, Defina M, Bocchia M.

Ann Hematol. 2009 Oct;88(10):1045.

 

2) Lenalidomide on alternative days is effective in myelodysplastic syndrome with 5q- deletion.

Defina M, Rondoni M, Gozzetti A, Aprile L, Chitarrelli I, Fabbri A, Lauria F, Bocchia M.

Br J Haematol. 2010 Feb;148(3):483-4.

 

3) Translocation(X;2)(q26;q11.2) in a patient with acute myeloid leukemia M2 evolved from essential thrombocytemia.

Gozzetti A, Crupi R, Rondoni M, Daviddi B, Defina M, Bocchia M, Pietrini A, Raspadori D, Lauria F.

Cancer Genet Cytogenet. 2010 Feb;197(1):84-5

 

4) Hyperlipidemic myeloma.

Gozzetti A, Defina M, Bocchia M, Lauria F.

Ann Hematol. 2010 Sep;89(9):939-40.

 

5) Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia.

Zaja F, Baccarani M, Mazza P, Bocchia M, Gugliotta L, Zaccaria A, Vianelli N, Defina M, Tieghi A, Amadori S, Campagna S, Ferrara F, Angelucci E, Usala E, Cantoni S, Visani G, Fornaro A, Rizzi R, De Stefano V, Casulli F, Battista ML, Isola M, Soldano F, Gamba E, Fanin R.

Blood. 2010 Apr 8;115(14):2755-62.

 

6) Very late relapse in a patient with chronic myeloid leukemia in sustained complete cytogenetic response under imatinib.

Defina M, Gozzetti A, Rondoni M, Aprile L, Ippoliti M, Chitarrelli I, Lauria F, Bocchia M. Leukemia Research. 2010 Aug;34(8):e215-6

 

7) Safety and efficacy of bortezomib, melphalan and low doses dexamethasone (VM-dex) in newly diagnosed patients with multiple myeloma.

Gozzetti A, Defina M, Bocchia M, Fabbri A, Marchini E, Chitarrelli I, Lauria F.

Leuk Res. 2010 Nov;34(11):e288-9.

 

8) Low-dose rituximab in adult patients with primary immune thrombocytopenia.

Zaja F, Vianelli N, Volpetti S, Battista ML, Defina M, Palmieri S, Bocchia M, Medeot M, De Luca S, Ferrara F, Isola M, Baccarani M, Fanin R.

Eur J Haematol. 2010 Oct;85(4):329-34.

 

9) Reduction of imatinib dose and persistence of complete molecular response after p210 multipeptide vaccine in chronic myeloid leukaemia treated with dose escalation for acquired resistance.

Breccia M, Bocchia M, Cannella L, Defina M, Ippoliti M, Loglisci G, Santopietro M, Lauria F, Alimena G.

Br J Haematol. 2010 Jul;150(2):240-2.

 

10) Hyperlipidemia in a myeloma patient after bortezomib treatment.

Gozzetti A, Fabbri A, Defina M, Chitarrelli I, Bocchia M.

Leuk Res. 2010 Sep;34(9):e250.

 

11) Weekly bortezomib, pegylated liposomal doxorubicin, and dexamethasone is a safe and effective therapy for elderly patients with relapsed/refractory multiple myeloma.

Gozzetti A, Fabbri A, Oliva S, Marchini E, Bocchia M, Defina M, Lauria F.

Clin Lymphoma Myeloma Leuk. 2010 Feb;10(1):68-72.

 

12) A der(1)t(1;21)(p36.3;q22) in a patient with acute myelogenous leukemia M2.

Gozzetti A, Crupi R, Rondoni M, Defina M, Bocchia M, Pietrini A, Raspadori D, Lauria F.

Acta Haematol. 2010;124(1):44-5. Epub 2010 Jul 3.

 

13) Complete molecular response in CML after p210 BCR-ABL1-derived peptide vaccination.

Bocchia M, Defina M, Aprile L, Ippoliti M, Crupi R, Rondoni M, Gozzetti A, Lauria F.

Nat Rev Clin Oncol. 2010 Oct;7(10):600-3.

 

14) Lenalidomide efficacy in bortezomib-resistant myeloma.

Gozzetti A, Crupi R, Defina M, Bocchia M.

Nat Rev Clin Oncol. 2010 Sep;7(9).

 

15)Unusual localizations of plasmacytoma.

Gozzetti A, Coviello G, Fabbri A, Della Corte R, Bocchia M, Defina M, Lauria F.

Leuk Res. 2011 Jul;35(7):e104-5.

 

16) A central nervous system CD56 positive multiple myeloma patient with a t(11;14) (q11;q32): a case report.

Gozzetti A, Cerase A, Crupi R, Raspadori D, Defina M, Bocchia M, Lauria F.

Leuk Res. 2011 Nov;35(11):e206-8.

 

17) Extramedullary multifocal plasmacytoma relapse in multiple myeloma.

Gozzetti A, Marchini E, Banchi B, Papini G, Defina M, Bocchia M, Lauria F.

Leuk Res. 2012 Jan;36(1):e34-6.

 

18) Plasmacytoma of the skull.

Gozzetti A, Cerase A, Defina M, Bocchia M.

Eur J Haematol. 2012 Apr;88(4):369.

 

19) Efficacy of bortezomib, lenalidomide and dexamethasone (VRD) in secondary plasma cell leukaemia.

Gozzetti A, Musto P, Defina M, D'Auria F, Papini G, Steduto T, D'Arena G, Bocchia M.

Br J Haematol. 2012 Feb 1.

 

20) Evaluation of residual CD34+Ph+ progenitor cells in chronic myeloid leukemia patients in complete cytogenetic response during first line nilotinib therapy.  Marzia Defina, Micaela Ippoliti, Alessandro Gozzetti, Elisabetta Abruzzese, Fausto Castagnetti, Rosaria Crupi, Mario Tiribelli, Massimo Breccia, Marzia Salvucci, Lara Aprile, Claudia Baratè, Antonella Gozzini, Gianantonio Rosti, Francesco Lauria and Monica Bocchia. Cancer. 2012. In press

 

21) Extramedullary myeloma relapses.

Gozzetti A, Papini G, Defina M, Bocchia M.

Ann Hematol. 2012 Feb 25.