1. Mihich
E, Pandolfi PP, Livingston D. Twenty-first annual Pezcoller Symposium:
Unconventional Therapeutic Targets in Cancer.Cancer Res. 2010 Jan
1;70(1):14-7.
2. Alonzo ES, Gottschalk RA, Das J, Egawa T, Hobbs RM, Pandolfi PP,
Pereira P, Nichols KE, Koretzky GA, Jordan MS, Sant'Angelo DB.
Development of promyelocytic zinc finger and ThPOK-expressing innate
gamma delta T cells is controlled by strength of TCR signaling and Id3.
J Immunol. 2010 Feb 1;184(3):1268-79.
3. Ciraolo E, Morello F, Hobbs RM, Wolf F, Marone R, Iezzi M, Lu X,
Mengozzi G, Altruda F, Sorba G, Guan K, Pandolfi PP, Wymann MP, Hirsch
E. Essential role of the p110beta subunit of phosphoinositide 3-OH
kinase in male fertility. Mol Biol Cell. 2010 Mar 1;21(5):704-11.
4. Nie D, Di Nardo A, Han JM, Baharanyi H, Kramvis I, Huynh T, Dabora S,
Codeluppi S, Pandolfi PP, Pasquale EB, Sahin M. Tsc2-Rheb signaling
regulates EphA-mediated axon guidance. Nat Neurosci. 2010 Feb;13(2):163-72.
5. Berger AH, Niki M, Morotti A, Taylor BS, Socci ND, Viale A, Brennan
C, Szoke J, Motoi N, Rothman PB, Teruya-Feldstein J, Gerald WL, Ladanyi
M, Pandolfi PP. Identification of DOK genes as lung tumor suppressors.
Nat Genet. 2010 Mar;42(3):216-23.
6. Alimonti A, Nardella C, Chen Z, Clohessy JG, Carracedo A, Trotman LC,
Cheng K, Varmeh S, Kozma SC, Thomas G, Rosivatz E, Woscholski R,
Cognetti F, Scher HI, Pandolfi PP. A novel type of cellular senescence
that can be enhanced in mouse models and human tumor xenografts to
suppress prostate tumorigenesis. J Clin Invest. 2010 Mar
1;120(3):681-93.
7. Ferretti R, Palumbo V, Di Savino A, Velasco S, Sbroggiò M,
Sportoletti P, Micale L, Turco E, Silengo L, Palumbo G, Hirsch E,
Teruya-Feldstein J, Bonaccorsi S, Pandolfi PP, Gatti M, Tarone G,
Brancaccio M. Morgana/chp-1, a ROCK inhibitor involved in centrosome
duplication and tumorigenesis. Dev Cell. 2010 Mar 16;18(3):486-95.
8. Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J,
Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP.
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular
senescence. Nature. 2010 Mar 18;464(7287):374-9.
9. Fagoonee S, Hobbs RM, De Chiara L, Cantarella D, Piro RM, Tolosano E,
Medico E, Provero P, Pandolfi PP, Silengo L, Altruda F. Generation of
functional hepatocytes from mouse germ line cell-derived pluripotent
stem cells in vitro. Stem Cells Dev. 2010 Aug;19(8):1183-94.
10. Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI,
Kang HY, Huang HY, Hung MC, Pandolfi PP, Lin HK. Deciphering the
transcriptional complex critical for RhoA gene expression and cancer
metastasis. Nat Cell Biol. 2010 May;12(5):457-67.
11. Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, Hobbs RM,
Sportoletti P, Varmeh S, Egia A, Fedele G, Rameh L, Loda M, Pandolfi PP.
Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic
PTEN-targeting intron that cooperates with its host gene MCM7 in
transformation. Sci Signal. 2010 Apr 13;3(117).
12. Alimonti A, Carracedo A, Clohessy JG, Trotman LC, Nardella C, Egia
A, Salmena L, Sampieri K, Haveman WJ, Brogi E, Richardson AL, Zhang J,
Pandolfi PP. Subtle variations in Pten dose determine cancer
susceptibility. Nat Genet. 2010 May;42(5):454-8.
13. Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. A
coding-independent function of gene and pseudogene mRNAs regulates
tumour biology. Nature. 2010 Jun 24;465(7301):1033-8.
14. Furic L, Rong L, Larsson O, Koumakpayi IH, Yoshida K, Brueschke A,
Petroulakis E, Robichaud N, Pollak M, Gaboury LA, Pandolfi PP, Saad F,
Sonenberg N. eIF4E phosphorylation promotes tumorigenesis and is
associated with prostate cancer progression. Proc Natl Acad Sci U S A.
2010 Aug 10;107(32):14134-9.
15. Hobbs RM, Seandel M, Falciatori I, Rafii S, Pandolfi PP. Plzf
regulates germline progenitor self-renewal by opposing mTORC1.Cell. 2010
Aug 6;142(3):468-79.
16. De Keersmaecker K, Real PJ, Gatta GD, Palomero T, Sulis ML, Tosello
V, Van Vlierberghe P, Barnes K, Castillo M, Sole X, Hadler M, Lenz J,
Aplan PD, Kelliher M, Kee BL, Pandolfi PP, Kappes D, Gounari F, Petrie
H, Van der Meulen J, Speleman F, Paietta E, Racevskis J, Wiernik PH,
Rowe JM, Soulier J, Avran D, Cavé H, Dastugue N, Raimondi S, Meijerink
JP, Cordon-Cardo C, Califano A, Ferrando AA
The TLX1 oncogene drives aneuploidy in T cell transformation. Nat Med.
2010 Nov;16(11):1321-7.
17. Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska
M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C,
Pinton P, Pandolfi PP
PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium
Release.Science. 2010 Oct 28.
18. Berger AH, Pandolfi PP. Haplo-insufficiency: a driving force in
cancer.J Pathol. 2010 Oct 6.
19. Maeda T, Ito K, Merghoub T, Poliseno L, Hobbs RM, Wang G, Dong L,
Maeda M, Dore LC, Zelent A, Luzzatto L, Teruya-Feldstein J, Weiss MJ,
Pandolfi PP. LRF is an essential downstream target of GATA1 in erythroid
development and regulates BIM-dependent apoptosis. Dev Cell. 2009
Oct;17(4):527-40.
20. Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A,
Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi
PP. Differential p53-independent outcomes of p19(Arf) loss in
oncogenesis. Sci Signal. 2009 Aug 18;2(84).
21. Cheng K, Sportoletti P, Ito K, Clohessy JG, Teruya-Feldstein J,
Kutok JL, Pandolfi PP. The cytoplasmic NPM mutant induces
myeloproliferation in a transgenic mouse model. Blood. 2009 Aug 7.
22. Gewinner C, Wang ZC, Richardson A, Teruya-Feldstein J,
Etemadmoghadam D, Bowtell D, Barretina J, Lin WM, Rameh L, Salmena L,
Pandolfi PP, Cantley LC. Evidence that inositol polyphosphate
4-phosphatase type II is a tumor suppressor that inhibits PI3K
signaling. Cancer Cell. 2009 Aug 4;16(2):115-25.
23. Kreslavsky T, Savage AK, Hobbs R, Gounari F, Bronson R, Pereira P,
Pandolfi PP, Bendelac A, von Boehmer H. TCR-inducible PLZF transcription
factor required for innate phenotype of a subset of gammadelta T cells
with restricted TCR diversity. Proc Natl Acad Sci U S A. 2009 Jul
28;106(30):12453-8. Epub 2009 Jul 15.
24. Xu D, Holko M, Sadler AJ, Scott B, Higashiyama S, Berkofsky-Fessler
W, McConnell MJ, Pandolfi PP, Licht JD, Williams BR. Promyelocytic
leukemia zinc finger protein regulates interferon-mediated innate
immunity. Immunity. 2009 Jun 19;30(6):802-16.
25. Gutierrez A, Sanda T, Grebliunaite R, Carracedo A, Salmena L, Ahn Y,
Dahlberg S, Neuberg D, Moreau LA, Winter SS, Larson R, Zhang J,
Protopopov A, Chin L, Pandolfi PP, Silverman LB, Hunger SP, Sallan SE,
Look AT. High frequency of PTEN, PI3K, and AKT abnormalities in T-cell
acute lymphoblastic leukemia. Blood. 2009 Jul 16;114(3):647-50.
26. Salazar M, Carracedo A, Salanueva IJ, Hernández-Tiedra S, Lorente M,
Egia A, Vázquez P, Blázquez C, Torres S, García S, Nowak J, Fimia GM,
Piacentini M, Cecconi F, Pandolfi PP, González-Feria L, Iovanna JL,
Guzmán M, Boya P, Velasco G. Cannabinoid action induces
autophagy-mediated cell death through stimulation of ER stress in human
glioma cells. J Clin Invest. 2009 May;119(5):1359-72.
27. Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A,
Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W,
Pandolfi PP. Aberrant ERG expression cooperates with loss of PTEN to
promote cancer progression in the prostate. Nat Genet. 2009
May;41(5):619-24.
28. Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J,
Corcoran M, Björklund AC, Hultenby K, Lundin J, Heyman M, Söderhäll S,
Mazur J, Porwit A, Pandolfi PP, Zhivotovsky B, Panaretakis T, Grandér D.
Cell death induced by dexamethasone in lymphoid leukemia is mediated
through initiation of autophagy. Cell Death Differ. 2009
Jul;16(7):1018-29.
29. Clohessy JG, Pandolfi PP. beta-tting on p63 as a metastatic
suppressor. Cell. 2009 Apr 3;137(1):28-30.
30. Fumagalli S, Di Cara A, Neb-Gulati A, Natt F, Schwemberger S, Hall
J, Babcock GF, Bernardi R, Pandolfi PP, Thomas G. Absence of nucleolar
disruption after impairment of 40S ribosome biogenesis reveals an
rpL11-translation-dependent mechanism of p53 induction. Nat Cell Biol.
2009 Apr;11(4):501-8. Epub 2009 Mar 15.
31. Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL,
Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP.
Phosphorylation-dependent regulation of cytosolic localization and
oncogenic function of Skp2 by Akt/PKB. Nat Cell Biol. 2009
Apr;11(4):420-32.
32. Distefano G, Boca M, Rowe I, Wodarczyk C, Ma L, Piontek KB, Germino
GG, Pandolfi PP, Boletta A. Polycystin-1 regulates extracellular
signal-regulated kinase-dependent phosphorylation of tuberin to control
cell size through mTOR and its downstream effectors S6K and 4EBP1. Mol
Cell Biol. 2009 May;29(9):2359-71.
33. Ito K, Bernardi R, Pandolfi PP. A novel signaling network as a
critical rheostat for the biology and maintenance of the normal stem
cell and the cancer-initiating cell. Curr Opin Genet Dev. 2009
Feb;19(1):51-9.
34. Carver BS, Tran J, Chen Z, Carracedo-Perez A, Alimonti A, Nardella
C, Gopalan A, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP. ETS
rearrangements and prostate cancer initiation. Nature. 2009 Feb
12;457(7231):E1; discussion E2-3.
35. Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z,
Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G,
Cordon-Cardo C, Pandolfi PP. Differential requirement of mTOR in
postmitotic tissues and tumorigenesis. Sci Signal. 2009 Jan 27;2(55)
36. Lapi E, Di Agostino S, Donzelli S, Gal H, Domany E, Rechavi G,
Pandolfi PP, Givol D, Strano S, Lu X, Blandino G.PML, YAP, and p73 are
components of a proapoptotic autoregulatory feedback loop. Mol Cell.
2008 Dec 26;32(6):803-14.
37. Carracedo A, Baselga J, Pandolfi PP. Deconstructing
feedback-signaling networks to improve anticancer therapy with mTORC1
inhibitors. Cell Cycle. 2008 Dec 15;7(24):3805-9. Epub 2008 Dec 22.
Review.
38. Nasr R, Guillemin MC, Ferhi O, Soilihi H, Peres L, Berthier C,
Rousselot P, Robledo-Sarmiento M, Lallemand-Breitenbach V, Gourmel B,
Vitoux D, Pandolfi PP, Rochette-Egly C, Zhu J, de Thé H. Eradication of
acute promyelocytic leukemia-initiating cells through PML-RARA
degradation. Nat Med. 2008 Dec;14(12):1333-1342.
39. Li L, Dutra A, Pak E, Labrie Iii JE, Gerstein RM, Pandolfi PP, Recht
LD, Ross AH. EGFRvIII expression and PTEN loss synergistically induce
chromosomal instability and glial tumors. Neuro Oncol. 2008 Sep 23.
40. Maggi LB Jr, Kuchenruether M, Dadey DY, Schwope RM, Grisendi S,
Townsend RR, Pandolfi PP, Weber JD. Nucleophosmin serves as a
rate-limiting nuclear export chaperone for the Mammalian ribosome. Mol
Cell Biol. 2008 Dec;28(23):7050-65.
41. Shima Y, Shima T, Chiba T, Irimura T, Pandolfi PP, Kitabayashi I.
PML activates transcription by protecting HIPK2 and p300 from
SCFFbx3-mediated degradation. Mol Cell Biol. 2008 Dec;28(23):7126-38.
42. Teitell MA, Pandolfi PP. Molecular Genetics of Acute Lymphoblastic
Leukemia. Annu Rev Pathol. 2008 Sep 10.
43. Cheng S, Hsia CY, Feng B, Liou ML, Fang X, Pandolfi PP, Liou HC.
BCR-mediated apoptosis associated with negative selection of immature B
cells is selectively dependent on Pten. Cell Res. 2008 Sep 9.
44. Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti
A, Egia A, Sasaki AT, Thomas G, Kozma SC, Papa A, Nardella C, Cantley
LC, Baselga J, Pandolfi PP. J Clin Invest. 2008
Sep;118(9):3065-74.Inhibition of mTORC1 leads to MAPK pathway activation
through a PI3K-dependent feedback loop in human cancer.
45. Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, Teruya-Feldstein
J, Pandolfi PP. The deubiquitinylation and localization of PTEN are
regulated by a HAUSP-PML network. Nature. 2008 Oct 9;455(7214):813-7.
46. Nardella C, Chen Z, Salmena L, Carracedo A, Alimonti A, Egia A,
Carver B, Gerald W, Cordon-Cardo C, Pandolfi PP. Aberrant Rheb-mediated
mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic
events.Genes Dev. 2008 Aug 15;22(16):2172-7.
47. Kovalovsky D, Uche OU, Eladad S, Hobbs RM, Yi W, Alonzo E, Chua K,
Eidson M, Kim HJ, Im JS, Pandolfi PP, Sant'Angelo DB.The BTB-zinc finger
transcriptional regulator PLZF controls the development of invariant
natural killer T cell effector functions. Nat Immunol. 2008
Sep;9(9):1055-64.
48. Chen S, Ndhlovu LC, Takahashi T, Takeda K, Ikarashi Y, Kikuchi T,
Murata K, Pandolfi PP, Riccardi C, Ono M, Sugamura K, Ishii
N.Co-inhibitory roles for glucocorticoid-induced TNF receptor in
CD1d-dependent natural killer T cells. Eur J Immunol. 2008
Aug;38(8):2229-40.
49. Acetylation of PML is involved in histone deacetylase
inhibitor-mediated apoptosis. Hayakawa F, Abe A, Kitabayashi I, Pandolfi
PP, Naoe T J Biol Chem. 2008 Sep 5;283(36):24420-5.
50. Poliseno L, Pitto L, Simili M, Mariani L, Riccardi L, Ciucci A,
Rizzo M, Evangelista M, Mercatanti A, Pandolfi PP, Rainaldi G.The
proto-oncogene LRF is under post-transcriptional control of MiR-20a:
implications for senescence. PLoS One. 2008 Jul 2;3(7):e2542.
51. Ito K, Bernardi R, Morotti A, Matsuoka S, Saglio G, Ikeda Y,
Rosenblatt J, Avigan DE, Teruya-Feldstein J, Pandolfi PP.PML targeting
eradicates quiescent leukaemia-initiating cells. Nature. 2008 Jun
19;453(7198):1072-8.
52. Carracedo A, Salmena L, Pandolfi PP.SnapShot: PTEN signaling
pathways. Cell. 2008 May 2;133(3):550.e1.
53. Salmena L, Carracedo A, Pandolfi PP. Tenets of PTEN tumor
suppression. Cell. 2008 May 2;133(3):403-14.
54. Hambardzumyan D, Becher OJ, Rosenblum MK, Pandolfi PP,
Manova-Todorova K, Holland EC. PI3K pathway regulates survival of cancer
stem cells residing in the perivascular niche following radiation in
medulloblastoma in vivo. Genes Dev. 2008 Feb 15;22(4):436-48.
55. Klimek VM, Fircanis S, Maslak P, Guernah I, Baum M, Wu N, Panageas
K, Wright JJ, Pandolfi PP, Nimer SD. Tolerability, pharmacodynamics, and
pharmacokinetics studies of depsipeptide (romidepsin) in patients with
acute myelogenous leukemia or advanced myelodysplastic syndromes. Clin
Cancer Res. 2008 Feb 1;14(3):826-32.
56. Sportoletti P, Grisendi S, Majid SM, Cheng K, Clohessy JG, Viale A,
Teruya-Feldstein J, Pandolfi PP.Npm1 is a haploinsufficient suppressor
of myeloid and lymphoid malignancies in the mouse. Blood. 2008 Apr
1;111(7):3859-62. Epub 2008 Jan 22.
57. Janas ML, Hodson D, Stamataki Z, Hill S, Welch K, Gambardella L,
Trotman LC, Pandolfi PP, Vigorito E, Turner M. The effect of deleting
p110delta on the phenotype and function of PTEN-deficient B cells. J
Immunol. 2008 Jan 15;180(2):739-46.
58. O'Keeffe GW, Gutierrez H, Pandolfi PP, Riccardi C, Davies AM.
NGF-promoted axon growth and target innervation requires GITRL-GITR
signaling. Nat Neurosci. 2008 Feb;11(2):135-42.
59. Guidez F, Parks S, Wong H, Jovanovic JV, Mays A, Gilkes AF, Mills
KI, Guillemin MC, Hobbs RM, Pandolfi PP, de Thé H, Solomon E, Grimwade
D. RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI,
contributing to retinoid resistance in t(11;17) acute promyelocytic
leukemia. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18694-9.
60. Bernardi R, Pandolfi PP.Structure, dynamics and functions of
promyelocytic leukaemia nuclear bodies. Nat Rev Mol Cell Biol. 2007
Dec;8(12):1006-16. Review.
61. Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S,
Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A,
Valenzuela DM, Hobbs RM, Pandolfi PP, Rafii S. Generation of functional
multipotent adult stem cells from GPR125+ germline progenitors. Nature.
2007 Sep 20;449(7160):346-50.
62. Ma L, Teruya-Feldstein J, Bonner P, Bernardi R, Franz DN, Witte D,
Cordon-Cardo C, Pandolfi PP. Identification of S664 TSC2 phosphorylation
as a marker for extracellular signal-regulated kinase mediated mTOR
activation in tuberous sclerosis and human cancer. Cancer Res. 2007 Aug
1;67(15):7106-12.
63. Filipponi D, Hobbs RM, Ottolenghi S, Rossi P, Jannini EA, Pandolfi
PP, Dolci S.Repression of kit expression by Plzf in germ cells. Mol Cell
Biol. 2007 Oct;27(19):6770-81.
64. Hermann BP, Sukhwani M, Lin CC, Sheng Y, Tomko J, Rodriguez M,
Shuttleworth JJ, McFarland D, Hobbs RM, Pandolfi PP, Schatten GP, Orwig
KE.Characterization, cryopreservation, and ablation of spermatogonial
stem cells in adult rhesus macaques. Stem Cells. 2007 Sep;25(9):2330-8.
65. Yoshida H, Ichikawa H, Tagata Y, Katsumoto T, Ohnishi K, Akao Y,
Naoe T, Pandolfi PP, Kitabayashi I. PML-retinoic acid receptor alpha
inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in
myeloid differentiation. Mol Cell Biol. 2007 Aug;27(16):5819-34. Epub
2007 Jun 11.
66. Salmena L, Pandolfi PP.Changing venues for tumour suppression:
balancing destruction and localization by monoubiquitylation. Nat Rev
Cancer. 2007 Jun;7(6):409-13.
67. Hernando E, Charytonowicz E, Dudas ME, Menendez S, Matushansky I,
Mills J, Socci ND, Behrendt N, Ma L, Maki RG, Pandolfi PP, Cordon-Cardo
C. The AKT-mTOR pathway plays a critical role in the development of
leiomyosarcomas. Nat Med. 2007 Jun;13(6):748-53.
68. Maeda T, Merghoub T, Hobbs RM, Dong L, Maeda M, Zakrzewski J, van
den Brink MR, Zelent A, Shigematsu H, Akashi K, Teruya-Feldstein J,
Cattoretti G, Pandolfi PP.Regulation of B versus T lymphoid lineage fate
decision by the proto-oncogene LRF. Science. 2007 May
11;316(5826):860-6.
69. Shen WH, Balajee AS, Wang J, Wu H, Eng C, Pandolfi PP, Yin Y.
Essential role for nuclear PTEN in maintaining chromosomal
integrity.Cell. 2007 Jan 12;128(1):157-70.
70. Trotman LC, Wang X, Alimonti A, Chen Z, Teruya-Feldstein J, Yang H,
Pavletich NP, Carver BS, Cordon-Cardo C, Erdjument-Bromage H, Tempst P,
Chi SG, Kim HJ, Misteli T, Jiang X, Pandolfi PP. Ubiquitination
regulates PTEN nuclear import and tumor suppression. Cell. 2007 Jan
12;128(1):141-56.
71. Wang X, Trotman LC, Koppie T, Alimonti A, Chen Z, Gao Z, Wang J,
Erdjument-Bromage H, Tempst P, Cordon-Cardo C, Pandolfi PP, Jiang
X.NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Cell. 2007 Jan
12;128(1):129-39.
72. The promyelocytic leukemia protein functions as a negative regulator
of IFN-gamma signaling. Choi YH, Bernardi R, Pandolfi PP, Benveniste EN.
Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18715-20.
73. Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, Pandolfi PP,
Ruiz P, Unger T, Funke-Kaiser H. A novel signal transduction cascade
involving direct physical interaction of the renin/prorenin receptor
with the transcription factor promyelocytic zinc finger protein. Circ
Res. 2006 Dec 8;99(12):1355-66. Epub 2006 Nov 2.
74. Shen TH, Lin HK, Scaglioni PP, Yung TM, Pandolfi PP. The mechanisms
of PML-nuclear body formation. Mol Cell. 2006 Nov 3;24(3):331-9.
75. Bergmann S, Pandolfi PP. Giving blood: a new role for CD40 in
tumorigenesis. J Exp Med. 2006 Oct 30;203(11):2409-12.
76. Bernardi R, Guernah I, Jin D, Grisendi S, Alimonti A,
Teruya-Feldstein J, Cordon-Cardo C, Simon MC, Rafii S, Pandolfi PP. PML
inhibits HIF-1alpha translation and neoangiogenesis through repression
of mTOR. Nature. 2006 Aug 17;442(7104):779-85.
77. Savoia E, Fantini MP, Pandolfi PP, Dallolio L, Collina N. Assessing
the construct validity of the Italian version of the EQ-5D: preliminary
results from a cross-sectional study in North Italy. Health Qual Life
Outcomes. 2006 Aug 10;4:47.
78. Joe Y, Jeong JH, Yang S, Kang H, Motoyama N, Pandolfi PP, Chung JH,
Kim MK. ATR, PML, and CHK2 play a role in arsenic trioxide-induced
apoptosis. J Biol Chem. 2006 Sep 29;281(39):28764-71.
79. Scaglioni PP, Yung TM, Cai LF, Erdjument-Bromage H, Kaufman AJ,
Singh B, Teruya-Feldstein J, Tempst P, Pandolfi PP. A CK2-dependent
mechanism for degradation of the PML tumor suppressor. Cell. 2006 Jul
28;126(2):269-83.
80. Yang S, Jeong JH, Brown AL, Lee CH, Pandolfi PP, Chung JH, Kim MK.
Promyelocytic leukemia activates Chk2 by mediating Chk2
autophosphorylation. J Biol Chem. 2006 Sep 8;281(36):26645-54.
81. Grisendi S, Mecucci C, Falini B, Pandolfi PP. Nucleophosmin and
cancer. Nat Rev Cancer. 2006 Jul;6(7):493-505. Review.
82. Chen ML, Xu PZ, Peng XD, Chen WS, Guzman G, Yang X, Di Cristofano A,
Pandolfi PP, Hay N. The deficiency of Akt1 is sufficient to suppress
tumor development in Pten+/- mice. Genes Dev. 2006 Jun
15;20(12):1569-74.
83. Bai F, Pei XH, Pandolfi PP, Xiong Y. p18 Ink4c and Pten constrain a
positive regulatory loop between cell growth and cell cycle control. Mol
Cell Biol. 2006 Jun;26(12):4564-76.
84. Andrés V, Gascón-Irún M, Pandolfi PP, González-Navarro H. Atheroma
development in apolipoprotein E-null mice is not affected by partial
inactivation of PTEN. Front Biosci. 2006 Sep 1;11:2739-45.
85. Trotman LC, Alimonti A, Scaglioni PP, Koutcher JA, Cordon-Cardo C,
Pandolfi PP. Identification of a tumour suppressor network opposing
nuclear Akt function. Nature. 2006 May 25;441(7092):523-7.
86. Matsushita H, Scaglioni PP, Bhaumik M, Rego EM, Cai LF, Majid SM,
Miyachi H, Kakizuka A, Miller WH Jr, Pandolfi PP. In vivo analysis of
the role of aberrant histone deacetylase recruitment and RAR alpha
blockade in the pathogenesis of acute promyelocytic leukemia. J Exp Med.
2006 Apr 17;203(4):821-8.
87. Kashiwada M, Cattoretti G, McKeag L, Rouse T, Showalter BM, Al-Alem
U, Niki M, Pandolfi PP, Field EH, Rothman PB. Downstream of tyrosine
kinases-1 and Src homology 2-containing inositol 5'-phosphatase are
required for regulation of CD4+CD25+ T cell development. J Immunol. 2006
Apr 1;176(7):3958-65.
88. Zhao M, Janas JA, Niki M, Pandolfi PP, Van Aelst L. Dok-1
independently attenuates Ras/mitogen-activated protein kinase and
Src/c-myc pathways to inhibit platelet-derived growth factor-induced
mitogenesis. Mol Cell Biol. 2006 Apr;26(7):2479-89.
89. Shaffer DR, Pandolfi PP. Breaking the rules of cancer. Nat Med. 2006
Jan;12(1):14-5.
90. Pandolfi PP. The PML-nuclear body associated protein Daxx regulates
the cellular response to CD40. Cell Death Differ. 2005 Nov 25;
91. Maeda T, Hobbs RM, Pandolfi PP. The transcription factor Pokemon: a
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92. Wang J, Devgan V, Corrado M, Prabhu NS, El-Deiry WS, Riccardi C,
Pandolfi PP, Missero C, Dotto GP.Glucocorticoid-induced tumor necrosis
factor receptor is a p21Cip1/WAF1 transcriptional target conferring
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2005 Nov 11;280(45):37725-31.
93. Lin HK, Bergmann S, Pandolfi PP.Deregulated TGF-beta signaling in
leukemogenesis.Oncogene. 2005 Aug 29;24(37):5693-700. Review.
94. Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher
JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP.Crucial
role of p53-dependent cellular senescence in suppression of
Pten-deficient tumorigenesis.Nature. 2005 Aug 4;436(7051):725-30.
95. Ma L, Teruya-Feldstein J, Behrendt N, Chen Z, Noda T, Hino O,
Cordon-Cardo C, Pandolfi PP. Genetic analysis of Pten and Tsc2
functional interactions in the mouse reveals asymmetrical
haploinsufficiency in tumor suppressionGenes Dev. 2005 Aug
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96. Barna M, Pandolfi PP, Niswander L.Gli3 and Plzf cooperate in
proximal limb patterning at early stages of limb development.Nature.
2005 Jul 14;436(7048):277-81.
97. Bernassola F, Oberst A, Melino G, Pandolfi PP.The promyelocytic
leukaemia protein tumour suppressor functions as a transcriptional
regulator of p63.Oncogene. 2005 Oct 20;24(46):6982-6.
98. Grisendi S, Bernardi R, Rossi M, Cheng K, Khandker L, Manova K,
Pandolfi PP.Role of nucleophosmin in embryonic development and
tumorigenesis.Nature. 2005 Sep 1;437(7055):147-53.
99. Hu X, Pandolfi PP, Li Y, Koutcher JA, Rosenblum M, Holland EC.TOR
promotes survival and astrocytic characteristics induced by Pten/AKT
signaling in glioblastoma. Neoplasia. 2005 Apr;7(4):356-68.
100. Xiao A, Yin C, Yang C, Di Cristofano A, Pandolfi PP, Van Dyke
T.Somatic induction of Pten loss in a preclinical astrocytoma model
reveals major roles in disease progression and avenues for target
discovery and validation.Cancer Res. 2005 Jun 15;65(12):5172-80.
101. Oberst A, Rossi M, Salomoni P, Pandolfi PP, Oren M, Melino G,
Bernassola F.Regulation of the p73 protein stability and degradation.
Biochem Biophys Res Commun. 2005 Jun 10;331(3):707-12. Review.
102. Ma L, Chen Z, Erdjument-Bromage H, Tempst P, Pandolfi PP.
Phosphorylation and functional inactivation of TSC2 by Erk implications
for tuberous sclerosis and cancer pathogenesis.Cell. 2005 Apr
22;121(2):179-93.
103. Cairo S, De Falco F, Pizzo M, Salomoni P, Pandolfi PP, Meroni G.PML
interacts with Myc, and Myc target gene expression is altered in
PML-null fibroblasts.Oncogene. 2005 Mar 24;24(13):2195-203.
104. Maeda T, Hobbs RM, Merghoub T, Guernah I, Zelent A, Cordon-Cardo C,
Teruya-Feldstein J, Pandolfi PP.Role of the proto-oncogene Pokemon in
cellular transformation and ARF repression. Nature. 2005 Jan
20;433(7023):278-85.
105. Grisendi S, Pandolfi PP NPM mutations in acute myelogenous
leukemia. N Engl J Med. 2005 Jan 20;352(3):291-2.
106. Oki S, Limnander A, Yao PM, Niki M, Pandolfi PP, Rothman PB. Dok1
and SHIP act as negative regulators of v-Abl-induced pre-B cell
transformation, proliferation and Ras/Erk activation. Cell Cycle. 2005
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