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1)
A small molecule based on the pRb2/p130 spacer domain leads to
inhibition of cdk2 activity, cell cycle arrest and tumor growth
reduction in vivo.
Bagella L, Sun A, Tonini T, Abbadessa G, Cottone G, Paggi MG, De
Luca A, Claudio PP, Giordano A.
Oncogene.
2007 Mar 22;26(13):1829-39. Epub 2006 Oct 16.
2)
Epigenetic modulation of estrogen receptor-alpha by pRb family
proteins: a novel mechanism in breast cancer.
Macaluso M, Montanari M, Noto PB, Gregorio V, Bronner C, Giordano A.
Cancer
Res. 2007 Aug 15;67(16):7731-7.
3)
Role of geminin: from normal control of DNA replication to cancer
formation and progression?
Montanari M, Macaluso M, Cittadini A, Giordano A.
Cell Death
Differ. 2006 Jul;13(7):1052-6. Epub 2006 Apr 21.
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