Julien Ackermann
Nic Jones laboratory

Christie Hospital NHS Trust, Paterson Institute, Withington, Manchester, UK.

AP-1 Network Project

Curriculum Vitae

Private address: Wilmslow Road, Flat 7, Withington, M20 3QX, Manchester, UK.
Professional address: Christie Hospital NHS Trust, Paterson Institute, Withington, M20 4BX, Manchester, UK.
Prof. tel: 0044/ 0161446 3028

Schools/ courses followed:
1993-1997. Bachelor of Biology at the university of Lausanne.
· Certificate of animal biology in 1996.
· Certificate of immunology and biochemistry in 1997.
· Certificate of biochemistry: laboratory work in microbiology department at CHUV, Lausanne in 1997. ‘ Transcription regulation in the mouse mammary tumor virus’. Laboratory of Dr. Elena Buetti.
1997-1999. Master degree in microbiology at CHUV, Lausanne.
· ‘Application of an adenovirus for studying the transcriptional regulation of MMTV in B lymphocytes’. Laboratory of Dr. Elena Buetti.

1999-summer 2004. PhD thesis in the laboratory of Dr. Friedrich Beermann at the Swiss institute of experimental research in cancer, Epalinges.
· PhD thesis: ‘Establishment of a metastatic melanoma mouse model and phenotype analysis’.
· ‘cours du 3ème cycle’: cell cycle and cancer course; microarray analysis course; bioinformatics course.
· ‘cours romand de formation l’expérimentation animale’; ‘cours romand de perfectionnement en experimentation animale’.
Publications:
Foletti A, Ackermann J, Schmidt A, Hummler E, Beermann F. Absence of fibroblast growth factor 2 does not prevent tumor formation originating from the RPE. Oncogene. 2002 March 14;21(12):1841-7.
Ackermann J, Frutschi M, Kaloulis K, McKee T, Frutschi M, Trumpp A, Beermann F.
Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background. Cancer Res. 2005 May 15; 65(10):4005-11.
Ackermann J, Beermann F. The fibroblast growth factor-2 is not essential for melanoma formation in a transgenic mouse model. To be published in Pigment Cell Research.

Ethical training course:
In July 2006: I will have an experimental animal course

Language:
French, English, German

AP-1 Network Project


The transcription factor ATF2 is a downstream component of the p38 and JNK1/2 stress signalling pathways. Using an ATF2 straight and conditional KO mouse, we are interested in studying T cell development, as well as T cell activation upon stimulation by a variety of stress signals implicated in inflammation. We are also interested in skin carcinogenesis and skin homeostasis.